Report of the workflow results
1 The results as an interactive table
2 The results as sensitivity plots
3 The top 10 most sensitive clusters
Cluster 69 - 3 transcripts (~ 25% < 1.53 μg/L)
Driver GO terms :
KEGG pathways :
Wikipathways :
| id | external_gene_name | BMD.zSD | TF | trend |
|---|---|---|---|---|
| ENSDART00000186757.1 | chia.1 | 0.3 | FALSE | U |
| ENSDART00000050271.9 | hexb | 39.7 | FALSE | dec |
| ENSDART00000099847.5 | st3gal7 | 2.8 | FALSE | dec |
Cluster 43 - 9 transcripts (~ 25% < 1.95 μg/L)
Driver GO terms :
KEGG pathways : Retinol metabolism
Wikipathways :
| id | external_gene_name | BMD.zSD | TF | trend |
|---|---|---|---|---|
| ENSDART00000144335.2 | cyp27c1 | 7.3 | FALSE | inc |
| ENSDART00000018676.7 | cyp3c1 | 42.0 | FALSE | inc |
| ENSDART00000130130.4 | cyp3c3 | 1.2 | FALSE | U |
| ENSDART00000054228.6 | lrata | 37.8 | FALSE | inc |
| ENSDART00000152432.2 | lratb.2 | 1.9 | FALSE | inc |
| ENSDART00000127075.3 | ugt1b1 | 3.8 | FALSE | dec |
| ENSDART00000124017.3 | ugt2a7 | 2.5 | FALSE | dec |
| ENSDART00000162089.2 | ugt2a7 | 1.7 | FALSE | dec |
| ENSDART00000105604.5 | zgc:77938 | 2.9 | FALSE | dec |
Cluster 10 - 15 transcripts (~ 25% < 2.07 μg/L)
Driver GO terms : sphingolipid metabolic process
KEGG pathways : Sphingolipid metabolism
Wikipathways :
| id | external_gene_name | BMD.zSD | TF | trend |
|---|---|---|---|---|
| ENSDART00000146650.2 | asah2 | 1.34 | FALSE | dec |
| ENSDART00000013343.8 | b4galt6 | 38.51 | FALSE | dec |
| ENSDART00000025385.8 | cers2a | 25.77 | FALSE | dec |
| ENSDART00000172824.2 | cers3a | 1.74 | FALSE | dec |
| ENSDART00000011076.7 | cers5 | 2.59 | FALSE | dec |
| ENSDART00000075567.6 | enpp7.1 | 0.84 | FALSE | U |
| ENSDART00000150118.4 | gba2 | 1.39 | FALSE | dec |
| ENSDART00000022621.11 | kdsr | 2.40 | FALSE | dec |
| ENSDART00000083898.7 | plpp3 | 5.29 | FALSE | dec |
| ENSDART00000147420.2 | sgpl1 | 2.57 | FALSE | dec |
| ENSDART00000172269.2 | smpd3 | 49.35 | FALSE | dec |
| ENSDART00000164652.2 | SPHK1 | 36.01 | FALSE | dec |
| ENSDART00000171454.2 | sphk2 | 3.60 | FALSE | dec |
| ENSDART00000188829.1 | st6galnac4 | 23.11 | FALSE | dec |
| ENSDART00000183528.1 | ugt8 | 4.12 | FALSE | dec |
Cluster 37 - 5 transcripts (~ 25% < 2.19 μg/L)
Driver GO terms :
KEGG pathways :
Wikipathways :
| id | external_gene_name | BMD.zSD | TF | trend |
|---|---|---|---|---|
| ENSDART00000101304.5 | atg12 | 31.1 | FALSE | inc |
| ENSDART00000041304.8 | atg3 | 2.2 | FALSE | U |
| ENSDART00000113162.4 | pi4kaa | 42.3 | FALSE | dec |
| ENSDART00000101265.5 | pik3c3 | 3.9 | FALSE | inc |
| ENSDART00000015694.7 | rab5ab | 1.7 | FALSE | dec |
Cluster 86 - 3 transcripts (~ 25% < 2.34 μg/L)
Driver GO terms :
KEGG pathways :
Wikipathways :
| id | external_gene_name | BMD.zSD | TF | trend |
|---|---|---|---|---|
| ENSDART00000006099.9 | lims2 | 4.6 | FALSE | inc |
| ENSDART00000064187.7 | parvaa | 2.1 | FALSE | dec |
| ENSDART00000011751.9 | parvb | 2.6 | FALSE | inc |
Cluster 68 - 17 transcripts (~ 25% < 2.36 μg/L)
Driver GO terms :
KEGG pathways : Lysosome
Wikipathways :
| id | external_gene_name | BMD.zSD | TF | trend |
|---|---|---|---|---|
| ENSDART00000058339.7 | ap3s2 | 3.4 | FALSE | inc |
| ENSDART00000189874.1 | ap4s1 | 35.2 | FALSE | inc |
| ENSDART00000178932.2 | cltb | 2.8 | FALSE | dec |
| ENSDART00000062749.6 | cts12 | 52.4 | FALSE | dec |
| ENSDART00000060245.4 | ctsh | 33.8 | FALSE | inc |
| ENSDART00000034102.7 | ctss2.2 | 58.7 | FALSE | inc |
| ENSDART00000172292.2 | gga3b | 42.6 | FALSE | dec |
| ENSDART00000121714.5 | gnptab | 2.3 | FALSE | U |
| ENSDART00000141771.2 | gnptg | 37.4 | FALSE | inc |
| ENSDART00000139087.3 | lgmn | 1.5 | FALSE | U |
| ENSDART00000157619.2 | litaf | 43.3 | TRUE | inc |
| ENSDART00000146101.2 | mcoln1a | 2.8 | FALSE | dec |
| ENSDART00000126129.3 | nagpa | 1.9 | FALSE | dec |
| ENSDART00000163398.2 | pla2g15 | 2.4 | FALSE | dec |
| ENSDART00000058491.7 | ppt1 | 45.4 | FALSE | inc |
| ENSDART00000158192.2 | ppt2 | 2.2 | FALSE | bell |
| ENSDART00000142922.2 | slc17a5 | 3.5 | FALSE | dec |
Cluster 17 - 28 transcripts (~ 25% < 2.55 μg/L)
Driver GO terms : lipid biosynthetic process
KEGG pathways : Steroid biosynthesis
Wikipathways : Cholesterol biosynthesis
| id | external_gene_name | BMD.zSD | TF | trend |
|---|---|---|---|---|
| ENSDART00000130801.3 | acsl1b | 2.18 | FALSE | dec |
| ENSDART00000101126.5 | alox12 | 3.38 | FALSE | dec |
| ENSDART00000011076.7 | cers5 | 2.59 | FALSE | dec |
| ENSDART00000140882.2 | crppa | 18.97 | FALSE | inc |
| ENSDART00000043156.6 | cyp17a1 | 2.73 | FALSE | dec |
| ENSDART00000172882.2 | cyp27b1 | 3.01 | FALSE | dec |
| ENSDART00000190178.1 | dhcr7 | 2.41 | FALSE | dec |
| ENSDART00000179784.1 | ERG28 | 41.26 | FALSE | dec |
| ENSDART00000121859.3 | fa2h | 1.67 | FALSE | dec |
| ENSDART00000166508.2 | fdft1 | 1.49 | FALSE | dec |
| ENSDART00000078972.5 | fitm1l | 27.73 | FALSE | inc |
| ENSDART00000153390.2 | gpam | 30.83 | FALSE | dec |
| ENSDART00000159216.2 | hmgcs1 | 2.98 | FALSE | dec |
| ENSDART00000080925.4 | impad1 | 2.66 | FALSE | dec |
| ENSDART00000181004.1 | insig2 | 36.86 | FALSE | dec |
| ENSDART00000087241.6 | lss | 0.49 | FALSE | U |
| ENSDART00000034054.8 | nus1 | 28.81 | FALSE | dec |
| ENSDART00000144484.2 | PYURF | 7.37 | FALSE | inc |
| ENSDART00000065600.5 | sc5d | 2.28 | FALSE | dec |
| ENSDART00000141130.2 | scap | 37.09 | FALSE | dec |
| ENSDART00000046802.7 | sccpdha.1 | 1.98 | FALSE | dec |
| ENSDART00000149351.2 | scd | 23.97 | FALSE | inc |
| ENSDART00000135606.3 | si:dkey-205h13.1 | 3.42 | FALSE | inc |
| ENSDART00000079879.5 | si:dkey-91i10.3 | 3.26 | FALSE | dec |
| ENSDART00000188829.1 | st6galnac4 | 23.11 | FALSE | dec |
| ENSDART00000163477.3 | tamm41 | 34.60 | FALSE | inc |
| ENSDART00000183528.1 | ugt8 | 4.12 | FALSE | dec |
| ENSDART00000005923.7 | zgc:77375 | 34.02 | FALSE | dec |
Cluster 73 - 14 transcripts (~ 25% < 2.96 μg/L)
Driver GO terms : fatty acid transport
KEGG pathways : PPAR signaling pathway
Wikipathways : PPAR signaling pathway
| id | external_gene_name | BMD.zSD | TF | trend |
|---|---|---|---|---|
| ENSDART00000056745.6 | acox3 | 3.06 | FALSE | dec |
| ENSDART00000130801.3 | acsl1b | 2.18 | FALSE | dec |
| ENSDART00000088168.6 | CABZ01055347.1 | 26.93 | FALSE | dec |
| ENSDART00000050753.6 | cd36 | 0.38 | FALSE | U |
| ENSDART00000145375.5 | cpt1aa | 2.96 | FALSE | dec |
| ENSDART00000153935.2 | cyp8b2 | 2.21 | FALSE | dec |
| ENSDART00000033724.7 | fabp3 | 38.40 | FALSE | inc |
| ENSDART00000026180.9 | fabp7a | 3.60 | FALSE | inc |
| ENSDART00000041229.5 | fabp7b | 39.95 | FALSE | inc |
| ENSDART00000101918.5 | proca1 | 3.66 | FALSE | inc |
| ENSDART00000103491.5 | rbp7b | 17.67 | FALSE | inc |
| ENSDART00000149351.2 | scd | 23.97 | FALSE | inc |
| ENSDART00000079879.5 | si:dkey-91i10.3 | 3.26 | FALSE | dec |
| ENSDART00000170147.2 | slc27a4 | 2.98 | FALSE | dec |
Cluster 76 - 36 transcripts (~ 25% < 2.98 μg/L)
Driver GO terms : intracellular protein transport
KEGG pathways :
Wikipathways :
| id | external_gene_name | BMD.zSD | TF | trend |
|---|---|---|---|---|
| ENSDART00000140042.2 | ap1b1 | 35.91 | FALSE | dec |
| ENSDART00000170714.3 | ap1g1 | 43.08 | FALSE | dec |
| ENSDART00000135761.3 | ap1s2 | 49.21 | FALSE | inc |
| ENSDART00000046587.7 | ap2m1a | 32.77 | FALSE | inc |
| ENSDART00000139499.2 | ap2m1a | 2.24 | FALSE | dec |
| ENSDART00000058339.7 | ap3s2 | 3.43 | FALSE | inc |
| ENSDART00000189874.1 | ap4s1 | 35.23 | FALSE | inc |
| ENSDART00000002824.10 | appbp2 | 40.08 | FALSE | dec |
| ENSDART00000144920.3 | clta | 2.25 | FALSE | dec |
| ENSDART00000178932.2 | cltb | 2.76 | FALSE | dec |
| ENSDART00000011201.7 | copz1 | 32.50 | FALSE | inc |
| ENSDART00000023058.8 | efhc1 | 4.30 | FALSE | bell |
| ENSDART00000123935.4 | erbin | 31.50 | TRUE | dec |
| ENSDART00000182827.1 | gga1 | 51.01 | FALSE | dec |
| ENSDART00000172292.2 | gga3b | 42.59 | FALSE | dec |
| ENSDART00000142080.2 | kpna1 | 2.82 | FALSE | bell |
| ENSDART00000074519.4 | kpna3 | 2.48 | FALSE | dec |
| ENSDART00000066123.7 | kpna6 | 36.86 | FALSE | dec |
| ENSDART00000187730.1 | LO017722.1 | 28.03 | FALSE | dec |
| ENSDART00000110839.4 | mon1a | 2.03 | FALSE | dec |
| ENSDART00000124582.3 | napbb | 36.34 | FALSE | dec |
| ENSDART00000060853.5 | pex10 | 0.63 | FALSE | U |
| ENSDART00000183661.1 | pex14 | 3.77 | TRUE | dec |
| ENSDART00000060766.4 | rab11a | 4.30 | FALSE | dec |
| ENSDART00000055810.8 | rab1ba | 22.42 | FALSE | dec |
| ENSDART00000034124.8 | rab5aa | 36.94 | FALSE | dec |
| ENSDART00000100173.6 | ranbp3b | 29.35 | FALSE | dec |
| ENSDART00000177459.2 | RIC1 | 31.81 | FALSE | dec |
| ENSDART00000084598.6 | selenos | 3.23 | FALSE | U |
| ENSDART00000144925.3 | snx27a | 26.89 | FALSE | dec |
| ENSDART00000146275.3 | strada | 2.09 | FALSE | inc |
| ENSDART00000191347.1 | STRADB | 48.37 | FALSE | dec |
| ENSDART00000087797.5 | tgfbrap1 | 23.45 | FALSE | dec |
| ENSDART00000037183.6 | tmed2 | 1.76 | FALSE | dec |
| ENSDART00000067621.6 | vps37c | 32.36 | FALSE | dec |
| ENSDART00000187421.1 | zgc:77650 | 3.04 | FALSE | inc |
Cluster 42 - 4 transcripts (~ 25% < 3.01 μg/L)
Driver GO terms :
KEGG pathways :
Wikipathways :
| id | external_gene_name | BMD.zSD | TF | trend |
|---|---|---|---|---|
| ENSDART00000021009.9 | cbfa2t3 | 2.5 | FALSE | bell |
| ENSDART00000167759.2 | ldb1b | 31.6 | TRUE | dec |
| ENSDART00000044208.6 | lmo1 | 3.2 | TRUE | inc |
| ENSDART00000020529.9 | tcf3a | 35.7 | TRUE | dec |